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Children: AAP recommends 40 80 mg/kg daily (maximum 1 g daily) given in 3 or 4 divided doses for 5 10 days. Adolescents: CDC recommends 400 mg 3 times daily or 200 mg 5 times daily for 7 10 days; duration may be extended if healing is incomplete after 10 days. IV: 250 mg/m 2 /dose every 8 hours or 125 mg/m 2 /dose every 6 hours; maximum daily dose: 80 mg/kg/day Oral: 60 to 90 mg/kg/ day in 2 to 3 divided doses; maximum dose: 800 mg/dose twice daily Children and Adolescents 40 kg: There was a less than dose-proportional increase in acyclovir maximum concentration (Cmax) and area under the acyclovir concentration-time curve (AUC) after single-dose and multiple-dose administration (4 times daily) of VALTREX from doses between 250 mg to 1 gram. Each 400-mg tablet of acyclovir contains 400mg of acyclovir and the inactive ingredients magnesium stearate, microcrystalline cellulose, povidone and sodium starch glycolate. Acyclovir is a white, crystalline powder with the molecular formula C8H11N5O3 and a molecular weight of 225. The maximum solubility in water at 37 C is 2.5mg/mL. How obesity complicates medication dosing for clinicians: Two critical scenarios. As obesity prevalence increases, clinicians need clarity around providing Aster Online a leading pharmacy in UAE offers premium healthcare and wellness products. Buy OTC and prescription only medicines, supplements, vitamins

faroway Detailed Acyclovir dosage information for adults and children. Includes dosages for Herpes Simplex Labialis, Herpes Simplex – Suppression, Herpes Zoster and more; plus renal, liver and dialysis adjustments. Normal dosage 200 mg every 4 hours or 400 mg every 12 hours and CrCl less than 10 mL/min/1.73 m : Decrease to 200 mg every 12 hours; Normal dosage 800 mg every 4 hours and CrCl mL/min/1.73 m : Decrease to 800 mg every 8 hours; Normal dosage 800 mg every 4 hours and CrCl less than 10 mL/min/1.73 m : Decrease to 800 mg every 12 hours Typical dosage for reinfection (flare-up of the infection): 200 mg every 4 hours, five times per day, for 5 days. You should take this drug as soon as the first 2 to less than 18 years: 20 mg/kg orally 3 times a day for 5 days Maximum dosage: 1 g orally 3 times a day Comments: Therapy should be started at the earliest sign/symptom of chickenpox, within 24 hours after onset of rash. An oral suspension may be prepared extemporaneously for use in patients for whom the tablet formulation is not appropriate. Acyclovir is a small drug MW 225 Da with a low plasma protein binding, volume of distribution of 0.6 L/kg, and a partition coefficient (log P) of -1.56 denoting a hydrophilic nature. Maximum solubility at physiological pH is 2.5 mg/ml. Acyclovir is distributed into the lean body compartment.

Children up to 12 years of age Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days.